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Tirzepatide carries the highest risk of diarrhea in type 2 diabetes patients, while semaglutide has the highest risk for constipation

Blood glucose was recorded at the indicated time-points from the tail vein using a hand-held glucometer (GlucoRx Nexus)

4, genetically proxied BMI, ISI, HDL-C, and TG were significantly associated with an increased risk of MASLD both in the discovery dataset and the replication dataset

And again, I just really want to emphasize that point that I think that a lot of focus has been on weight with these medications, but I encourage people to familiarize themselves with additional data around the cardiovascular benefits, reductions in things like heart attacks and strokes, reductions in fatty liver, protection of the kidneys and diabetes