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These results may lead to greater adherence to the oral formulation of SMG and thus increase the popularity of this drug as long as there is no significant increase in adverse effects

BEL 1 Recommendation 13.5 The ideal insulin regimen should be personalized to an individuals needs and glycemic targets, attempting to better emulate physiological insulin replacement to maintain near normoglycemia, to prevent the development and progression of DM complications, while minimizing hypoglycemia and providing flexibility for specific daily life situations/scenarios such as: exercise, sleep, acute illness, psychological stress, etc

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Patients with specific GIPR and GLP1R genetic profiles may theoretically benefit from dual-receptor agonism more robustly than single-receptor therapy, though individual response depends on many factors beyond genetics