10.1371/journal.pone.0097788 Summary Keywords anti-inflammatory effects, antioxidant properties, beta-adrenoreceptor antagonists, -blockers, carvedilol, metabolic diseases, glucose control, nebivolol Citation Drygaa S, Radzikowski M and Maciejczyk M (2024) -blockers and metabolic modulation: unraveling the complex interplay with glucose metabolism, inflammation and oxidative stress
( B ) Liver-specific Chac1 overexpression using AAV8
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These data indicate FASN was downregulated at the posttranslational level by oxidation-induced protein degradation due to GSH depletion