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45 In showing significant associations between latitude as a surrogate measure of UVR and the frequency of four gene polymorphisms that influence folate cofactor partitioning in folate metabolism, the present findings may provide new insight into folate-related diseases

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HOW TO USE: Apply a thin layer of this Serum directly to brown spots on dry, cleansed skin, preferably at night, This Serum evens out skin tone PROTECT YOUR SKIN - Follow up with minimum SPF 30 sun protection daily during and after treatment in order to avoid further pigmentation.