The reductions in lean mass do not necessarily indicate pathological muscle loss, as improvements in body composition, physical function, and quality of life have been reported with semaglutide and tirzepatide in subanalyses of the STEP-1 and SURMOUNT-1 programs [7,8]
In laboratory research, GHK-Cu is used as a biochemical tool to study copper-dependent signaling pathways, extracellular matrix (ECM) regulation, redox balance, and transcriptional modulation in controlled in vitro and preclinical experimental models
Together, their actions may create a stronger foundation for overall cellular stability and healthy aging pathways
However, because they are not yet FDA-approved for medical use, access is typically through compounding pharmacies or clinical research settings