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The jump from 0.5 mg to 1.0 mg is the largest proportional increase in the entire titration schedule, doubling your dose again

As a primary BA sensor, the canonical function of FXR is to maintain the BA pool homeostasis by regulating its synthesis, transport, and secretion

Potential Research Applications: Fat Metabolism: In obese animal models (e.g., Zucker rats), AOD 9604 reduced body weight gain by over 50% within 19 days (oral, 500 g/kg daily)

Having far more injections than your levels call for adds cost and appointments without a matching benefit, which is why frequency should track a confirmed need rather than a habit