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As obesity increasingly contributes to musculoskeletal disability, therapies addressing both weight and inflammation may become more central to osteoarthritis care

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The distinct second messenger signaling profiles observed for hGPR17L-V96M and mGPR17 relative to hGPR17L in HEK293 cells suggested that they could be used as molecular tools to evaluate the contributions of cAMP and calcium signaling to the regulation of GLP-1 secretion in GLUTag cells

For example, some pain relievers, like ibuprofen, contain sulfur, but they are not related to sulfa drugs and typically do not cause sulfa allergies