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[8] Methionine is the precursor to SAMe and it also has benefits on gut health, while people with bipolar disorder should not take SAMe except under the supervision of a health care provider, as SAMe may worsen symptoms of mania

The OC has been developed quite well in many experimental systems

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J Ethnopharmacol 145(2):554565 Aboulthana WM, Shousha WG, Essawy EA-R, Saleh MH, Salama AH (2021) Assessment of the anti-cancer efficiency of silver Moringa oleifera leaves nano-extract against colon cancer induced chemically in rats