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No acne treatment is permanent - just like no fat loss is every permanent if you overeat and no facelift can stop aging forever - circumstances can cause your acne to reappear months after a successful acne treatment - or even decades later

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This work is supported by the National Key Research & Development Program (2022YFC2603900), Beijing Natural Science Foundation (JQ24055), and the National Natural Science Foundation of China (22175189, 52373127)