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Common therapeutic supplements include vitamin D (crucial for immune tolerance), omega-3 fatty acids (modulate inflammatory signaling), glutathione precursors (support detoxification), zinc (supports gut barrier repair), quercetin (modulates mast cell activity), and specific probiotics selected to support immune regulation

Moreover, the SURMOUNTMMO (tirzepatide, NCT05556512) will assess the impact of the dual GLP-1/GIP RA in cardiovascular outcomes and all-cause mortality for people with obesity (without diabetes) when the REDEFINE-3 study will assess the impact of cagrisema in people with obesity (with and without T2DM) and established cardiovascular disease

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