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Dosage guidelines The recommendation of the British National Formulary is: Individual responses to neuroleptic drugs are very variable and to achieve optimum effect, dosage and dosage interval must be titrated according to the patients response. As mentioned in Chapter 3, The Royal College of Psychiatrists have issued the following advice on doses exceeding the British National Formulary upper limits (which constitutes unlicensed use)

Adding 2 mL to 50 mg gives a concentration of 25 mg/mL

However, these drugs cannot recognize a single mutation at the target site, and tumor cells easily acquire resistance against these drugs