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however, Fe deficiency may complicate these findings ( Znt10 KO mice, a model of systemic Mn overload, shows that intestinal Dmt1 deficiency reduced systemic Mn accumulation, indicating that DMT1 contributes to Mn overload in these mutant mice by promoting intestinal Mn absorption (Prajapati et al., 2025)

Lack of traceability : Compounded medications are not required to have the serial numbers (per the Drug Supply Chain Security Act) that FDA-approved medicines have

Riddell J, Shuman EM

However, it is our job to take the extra time to provide all of the facts and data during the informed consent process so that medical decisions are based on substantiated facts and not unsubstantiated fears