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From the miRNA target prediction, they selected mTOR as a candidate target and found that mTOR 3UTR bound directly to miR-99a/b using luciferase binding assay
These alcohol-metabolizing enzymes not only affect alcohol-associated liver disease (ALD), but may also modulate the pathogenesis of other liver diseases and cancer in the absence of alcohol consumption
The study did not establish causation, but the event illustrates why small trials cannot be described as proof of safety
Coxsackievirus and type 1 diabetes: diabetogenic mechanisms and implications for prevention
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