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Vitamin B12 injections may benefit people experiencing: Fatigue Vitamin B12 deficiency Low energy Poor absorption Pernicious anaemia Certain gastrointestinal conditions Vegan or vegetarian diets A consultation helps determine whether treatment is appropriate

What they found: Mean weight loss: 2.6 kg vs 2.3 kg placebo , a difference of only 0.3 kg (1 %) Statistically non-significant Clinically unsatisfactory for the obesity indication Safety profile remained favorable Why it matters: The study stopped the development of AOD-9604 as a drug