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Moreover, compared with Col-0, the GmMORF2a -overexpressing lines showed significantly lower levels in callose deposition, stomatal closing, ethylene production, accumulation of SA, and expression of basic immune marker genes and SA biosynthesis genes induced by PAMPs

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In terms of adverse drug reactions, aggregated data from phase II and III studies indicate that while dotinurad can potentially cause liver-related adverse reactions, such as hepatic steatosis and abnormal liver function tests, which the incidence is lower compared to benzbromarone

Here, it should be noted that the balance of two consecutive enzymatic reactions especially in the complex network of GSH biosynthesis is very important