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AbbVies Skyrizi reached $17.562 billion in 2025 sales and Rinvoq reached $8.304 billion, Sanofis Dupixent rose to 15.714 billion, and Novartis Kisqali climbed 58% to $4.783 billion

Its ability to influence areas of the brain related to addiction and reward can alter the brains response to alcohol and other drugs, diminishing the perceived reward and, consequently, the craving

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