glp 1 agonist metformin Clinical Focus on GLP-1 Agonists in Type 2 Diabetes Mellitus Role of GLP-1 Receptor Agonists

Therapy-induced senescent cells can re-enter the cell cycle to show aggressive proliferative and cancer stem-like properties, presenting a risk for recurrence and treatment resistance

According to data from the International Diabetes Federation, the global prevalence of DM among adults aged 2079 years reached 537 million in 2021, with projections indicating this number will rise to 693 million by 2045 (Lange et al., 1989

This reduces oxidative DNA damage within melanocytes, diminishing the triggers that upregulate melanin production in the first place

It invites readers to see medicine not merely as a science of intervention, but as a discipline of perception, empathy, and awarenessan approach essential for thoughtful practice in the 21st century