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While Bcl-2, an apoptosis inhibitor, is deactivated by the translocation of Bax, an apoptosis promoter, to the mitochondrial membrane, certain ion channels are formed in the membranes

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TANs can also suppress immune system function

Creation of isogenic cellular models for drug screening ( Currently, CRISPR is limited to in vitro and animal studies due to safety and ethical barriers, but advances in delivery vectors and base editing technologies may accelerate clinical translation ( 5.7 Artificial intelligence (AI) in diagnosis and monitoring AI and machine learning (ML) are revolutionizing PD management through: Early diagnosis : analyzing digital biomarkers (e.g., voice, gait, handwriting)