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For localized joint or tendon issues, subcutaneous injection near the injury site delivers high local concentrations while also providing systemic distribution

To validate mechanisms beyond speculative claims of oocyte quality, protocols should embed quantitative biomarkers, such as follicular fluid metabolomics, embryo morphology, mitochondrial function, or endometrial molecular signatures

doi:10.2337/dc11-s231 Jensterle M, Rizzo M, Haluzk M, Jane A