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doi: 10.1038/nrrheum.2010.196 21 Vander HeidenMGCantleyLCThompsonCB

The bigger concern is often GI side effects nausea, constipation which are manageable with slow titration

Each DEXA scan body fat report will allow you to calculate what fraction of your weight loss is fat vs

However, the foundational mechanism paper (Benoist et al., 2014 in J Pharmacol Exp Ther) establishing Dihexas HGF/c-Met pathway activation was formally retracted in April 2025 after being flagged since 2021