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6 This recent change in rhetoric on HRT may result in changes in prescribing practices resulting in a need for education on the different routes of administration for HRT, why a patient may choose one over another, and a need for information on switching between routes of administration

This cardiomyopathy is characterized by dysfunction of cardiac mitochondria, a decrease in plasma selenium, decreased cardiac GPx1 expression, increased oxidative stress in the myocardium as reflected by an increase in 8-hydroxy-2-deoxy-guanosine content of nuclei, and decreased whole blood GPx1 activity [24, 25]