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The divergence in the effect of mutagenesis of residues comprising the TM-binding pocket, even where interactions in the static consensus structures were similar, confirmed that static visualisation of complexes is insufficient to fully understand binding and activation mechanisms, and suggests that the dynamics of peptide-receptor engagement likely play a critical role
ApoB in particular is worth tracking it's a more direct measure of cardiovascular risk than standard LDL.Testing shows how much improvement you're actually getting
