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The other three treatment groups were represented approximately equally in the largest cluster, with a maximum of one animal per treatment group outside the cluster

The discovery that NNMT expression is dramatically elevated in adipose tissue of obese humans and animal models, and that NNMT inhibition or knockdown prevents diet-induced obesity and improves metabolic health, has catalyzed intense research interest in NNMT as a therapeutic target for obesity, metabolic syndrome, and related conditions

Or maybe its because NAC may prevent free radical damage and reduce oxidative stress and chronic inflammation (one adverse, downstream effect of the J A B)

Reactive Oxygen Species (ROS) inducible DNA cross-linking agents and their effect on cancer cells and normal lymphocytes