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While the first studies showing this were in mice [14], human studies have corroborated these findings [200], although its importance in relationship to traditional clearance pathways across the BBB and subarachnoidal granulations has been challenging to quantify

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Compared to the control group, the data obtained showed a nonsignificant change in the GLY level ( F (5, 24) = 2.655, p = 0.048, W = 0.592, p = 0.706) in the midbrain after one, seven, and fifteen days of IF (F1,F2 and F3 groups)

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