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Reviewed June 13, 2023

Less commonly discussed, joint pain has been reported by some patients

More research is needed to disentangle the effects of the medication from those of rapid weight loss itself

76,77 The mechanisms through which this occurs are not fully elucidated, although basic science and clinical studies have shown that GLP-1 agonists have immunomodulatory effects by reducing proinflammatory cytokines and altering immune cell populations