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Regular consultation with a nutritionist ensures the diet aligns with personal health goals

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Research ArticleMetabolismNeuroscience Free access | 10.1172/jci.insight.133429 1 Global Drug Discovery and 2 Global Research Technologies, Novo Nordisk A/S, Mlv, Denmark, and Seattle, Washington, USA

Liraglutide works by: Slowing gastric emptying , which prolongs the feeling of fullness after meals and may affect the absorption of some oral medicines Reducing appetite through effects on brain regions that regulate hunger Improving glycaemic control by enhancing insulin secretion and suppressing glucagon release (though Saxenda is licensed specifically for weight management, not diabetes treatment in the UK) Saxenda is licensed for adults with a body mass index (BMI) of 30 kg/m or greater, or 27 kg/m or greater in the presence of weight-related comorbidities, alongside a reduced-calorie diet and increased physical activity