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Our findings are in line with other observations suggesting that the ligature induced experimental periodontitis is a useful and highly reproducible model for gingival/periodontal inflammation (41, 42)

Ratios greater than 3 are highly suggestive of ALD

Behrens BC, Hamilton TC, Masuda H, Grotzinger KR, Whang-Peng J, Louie KG, Knutsen T, McKoy WM, Young RC, Ozols RF (1987) Characterization of a cis-diamminedichloroplatinum(II)-resistant human ovarian cancer cell line and its use in evaluation of platinum analogues

Beyond that diagnostic system, integrative clinicians often subgroup women with PCOS by dominant biology insulin-resistant, lean or adrenal-driven, or inflammatory and supplement choice tends to map more usefully to these biological subgroups than to the Rotterdam phenotype labels