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Platelets can produce a variety of anti-inflammatory cytokines, including IL-1 receptor antagonist (IL-1ra), soluble tumor necrosis factor (TNF-R) I and II, IL-4, IL-10, IL-13, and interferon

Previous studies have shown that selective depletion of synovial macrophages during experimental OA largely reduces cartilage damage and osteophyte formation, which are two major hallmarks of OA 48

This includes the elderly, pregnant and breastfeeding women, people who are taking the diabetes drug metformin, anyone who has had stomach or bowel surgery, or those who follow a strict vegan or vegetarian diet

And remember, dont blow on the area it can reintroduce bacteria