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How GHK-Cu Works (Mechanism of Action) GHK-Cu functions primarily as: A copper delivery molecule A modulator of gene expression A regulator of extracellular matrix remodelling Copper is an essential cofactor for enzymes involved in: Collagen cross-linking Angiogenesis Antioxidant defense Tissue remodelling GHK-Cu appears to: Increase synthesis of collagen types I and III Stimulate dermal fibroblast activity Modulate matrix metalloproteinases (MMPs) Reduce pro inflammatory signalling in wound models Its effects are local and tissue specific rather than systemic and hormonal

demonstrated an acute improvement in post meal glucose levels, despite no increases in insulin release

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Palaniyappan L, Liddle PF