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5 Figure 3: Pharmacy claims data show that 63% of patients initiating Wegovy or Zepbound in early 2024 remained on therapy at one year, up from 40% in the 2023 cohort

13 In the PIONEER-6 study, which compared oral semaglutide to placebo, retinopathy or adverse events related to DR occurred in 7.1% of semaglutide and 6.3% of placebo subjects

Naltrexone/bupropion (Contrave) is a medication that combines an opioid receptor antagonist (naltrexone) with a dopamine and norepinephrine reuptake inhibitor (bupropion)

Table of Contents What Is Retatrutide and Its Current Status in the UK What Bacteriostatic Water Is and Why It Is Used for Reconstitution Reconstitution of Retatrutide: Why This Should Only Occur in a Regulated Clinical Setting Risks and Safety Considerations You Should Be Aware Of Seeking Medical Guidance Before Using Unlicensed Peptides in the UK Scientific References Frequently Asked Questions What Is Retatrutide and Its Current Status in the UK Retatrutide is an unlicensed investigational drug in the UK with no MHRA or EMA marketing authorisation