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The elevated BCAAs catabolism in NSCLC cells suppresses m6A demethylase ALKBH5 expression, thereby promoting epithelial-mesenchymal transition and tumor metastasis (Mao et al., 2024)
Thus, investing in earlier diagnosis through genomic medicine, multidisciplinary expert centres and artificial intelligence is not simply good clinical practiceit is also a more efficient use of healthcare resources
Christopher Sparrow, a cardiologist specializing in heart failure and transplantation at OSF Saint Francis Medical Center in Peoria
FLS is also key in the pathophysiology of synovitis-arthritis due to its ability to express several proinflammatory mediators 7,8
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