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ADHD has a high degree of heritability, estimated at approximately 76%

The development of protein- and enzyme-based antioxidant drugs faces substantial challenges that are particularly problematic for chronic diseases like MS, including immunogenicity, high manufacturing and purification costs, limited stability, poor oral bioavailability, and unfavorable pharmacokinetic profiles that preclude long-term systemic administration ( 4.2 Pharmacodynamic and pharmacokinetic challenges of antioxidant drug development for MS Despite strong evidence implicating OS in the pathogenesis of MS, the development of antioxidant therapies has produced only limited and inconsistent clinical benefit