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Here, the population goes extinct before the alive cells can secrete sufficient glutathione to increase the probability of replicating, leading to no growth

As an upstream event of ferroptosis, autophagy activation can induce ferroptosis through different mechanisms, including NCOA4-mediated ferritin autophagy [95], RAB7A-mediated lipid autophagy [96], ARNTL-mediated biological clock protein autophagy [97], and BECN1-mediated System X c inhibition [64]

Monocyte-endothelial cell interactions in the regulation of vascular sprouting and liver regeneration in mouse

10.1038/cr.2010.178 74 MorrisD.GuerraC.DonohueC.OhH.KhurasanyM.VenketaramanV