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Partial and complete regression of breast cancer in patients in relation to dosage of coenzyme Q10 32

TQ inhibits -glucosidase and -amylase digestive enzymes, stimulates MAPK pathway activation that leads to an increase in muscle GLUT-4 levels, inhibits the activity of COX and lipoxygenase (LOX) enzymes, suppresses hepatic gluconeogenesis by targeting fructose-1,6-bisphosphatase and glucose-6-phosphatase, suppresses pro-inflammatory cytokines such as IL-6, TNF-, IFN- and IL-1, inhibits NO production, and reduces intestinal glucose absorption by inhibiting sodium-glucose linked transporter 1 (SLGT1) [98]

The reason for the lower ITP-modified adsorbed protein corona may be because ITP is embedded in the phospholipid layer, which would reduces its interaction with plasma proteins