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The gap is controlled human evidence

14.4 MOUNJARO Use in Combination with Basal Insulin with or without Metformin in Adult Patients with Type 2 Diabetes Mellitus SURPASS-5 (NCT04039503) was a 40-week double-blind trial that randomized 475 adult patients with type 2 diabetes mellitus with inadequate glycemic control on insulin glargine 100 units/mL, with or without metformin, to subcutaneous MOUNJARO 5 mg, MOUNJARO 10 mg, MOUNJARO 15 mg once weekly, or placebo

The exact dosage is dependent on medical condition, response to the treatment, age, and weight

Committee members nevertheless voted to recommend inclusion after considering available data as well as testimony from physicians, compounders and patients who argued that the peptide fulfills an unmet clinical need