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Graves disease: Graves disease is another autoimmune condition of the thyroid characterized by the production of TSIs that acts on TSH receptors found on the plasma membrane of thyroid follicular cells, triggering an excessive response by inducing a surge in secretion that eventually causes hyperthyroidism (Bartalena et al

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[32] This is to say, then, that the business of enhancing cognition in otherwise healthy subjects is rife with oft-unfulfilled promises and that claims of nootropic effect, especially those derived from findings in animal models of disease states or compromised cognition, should be approached with healthy skepticism