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This disparity is ascribed to variations in screening methodologies (eg, prevalent prostate-specific antigen [PSA] testing in affluent nations resulting in overdiagnosis), lifestyle determinants (eg, Western diets abundant in red meat and fat, obesity), aging demographics, and genetic predisposition (eg, elevated risk in populations of African descent)

The risk of substance use was also reduced The findings showed that GLP-1 medication use, especially semaglutide, was associated with fewer psychiatric-related hospitalizations and sick leave