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Half of the patients even started with two weeks of daily 5 mg B12 injections straight into the blood
For second half of study, administer one to two injections of 250mcg each
Depression: Some patients with mild to moderate depression might find Acupuncture point injection therapy (APIT) beneficial, especially when combined with other treatments
Appetite Effects The question about appetite is interesting because the proposed mechanism could reasonably go either direction: Reduced lipogenesis and improved metabolic flexibility could produce secondary effects on appetite regulation NAD+ restoration has complex effects on hypothalamic appetite signaling Preclinical data do not consistently describe dramatic appetite changes In human use were it to become clinically available patient-reported appetite effects would be a relevant monitoring parameter, but the data do not currently support a strong a priori expectation
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