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doi: 10.1080/10408398.2022.2107997 75

If I have fibromyalgia and IBS, is GLP-1 therapy safe

We tested this hypothesis by injecting Cre-dependent Gsto2 -short hairpin RNA (shRNA) or a scrambled-shRNA viral construct in the striatum of Trkb Penk -KO mice to allow expression of the shRNA specifically in enkephalinergic neurons at 3 months (Fig