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Clinicians should also monitor nutritional risks associated with rapid weight loss, such as deficiencies in iron, folic acid, and B vitamins, to ensure the patient is pregnancy-ready rather than just weight-ready. Given that GLP-1RAs improving IVF outcomes remains limited, their appropriate positioning remains a metabolic optimization tool before ART rather than a standardized pretreatment regimen (48)

For women of childbearing potential, it's important to note that GLP-1 receptor agonists are generally not recommended during pregnancy

Prior authorization requirements, eligibility monitoring and claims oversight all add complexity and, by extension, invisible costs to offering coverage

The highest tissue concentrations of free lipoic acid likely to be achieved through oral supplementation are at least 10 times lower than those of other intracellular antioxidants, such as vitamin C and glutathione