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They are often use in combination with topical treatments

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Situations Where Caution Is Warranted Certain conditions require careful evaluation before starting either compound: History of medullary thyroid carcinoma or MEN 2 syndrome (contraindication for Semaglutide) Active malignancy or history of certain cancers (growth hormone concerns) Severe gastrointestinal disorders Uncontrolled diabetes (requires careful management during treatment) Pregnancy or breastfeeding A thorough medical evaluation is essential before starting any peptide protocol