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Front Endocrinol (Lausanne) 4:

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Lipid-based nanoparticles, including solid lipid nanoparticles and nanoemulsions, have demonstrated enhanced protection of SFN from degradation in the gastrointestinal tract, while polymeric nanoparticles such as PLGA-based systems enable sustained release profiles that maintain therapeutic concentrations over extended periods

(PubMed) Batra S, Sahu RP, Kandala PK, Srivastava SK