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Preclinical pharmacokinetics, tolerability, and pharmacodynamics of metuzumab, a novel CD147 human-mouse chimeric and glycoengineered antibody

Nach der Rekonstitution (Mischen mit bakteriostatischem Wasser) empfehlen wir jedoch dringend die sachgeme Lagerung im Khlschrank.

Elife 9 , e54166 (2020)

Following repeated oral exposure for 4 weeks (1.75, 7, 28 mg/kg/day), granulomatous inflammation was observed, characterised by infiltration of macrophages and occasional lymphocytes into terminal bronchioles and alveolar spaces