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Here, we report the clinical and molecular features of 20 additional individuals who have been diagnosed with clEDS

Key Takeaways: PRP as a First-Line Injection for Knee Osteoarthritis Stronger and longer-lasting pain relief than HA and corticosteroid injections Reduces inflammation and promotes cartilage repair , rather than just masking symptoms Potential to slow OA progression , making it a disease-modifying therapy Fewer side effects compared to corticosteroids, which can accelerate cartilage loss with repeated use Given the growing body of high-level clinical evidence , PRP is increasingly being recommended as a first-line regenerative therapy for knee osteoarthritis, offering a biological approach to symptom management and disease modification

Non-negotiable every morning, indoors or not, with particular attention to the 72 hours after a session

"CV" (PDF)