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Overall, across the two repeat experiments for Cagri and CagriBB bound to the CTR, the conformational equilibrium between the bypass vs CT-like state was similar, suggesting that the salt bridge/ionic lock is sufficient to preferentially stabilize the bypass conformation at CTR (Supplementary Fig

In HepG2 cells, L-carnitine reduced free fatty acid-induced apoptosis (72), while similar anti-apoptotic effects occurred in oleic acid-treated hepatocytes (77)

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