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Albiglutide comprises two copies of GLP-1 fused as tandem repeats to the N terminus of albumin [3], while dulaglutide is a recombinant fusion protein consisting of two GLP-1 peptides covalently linked to a human IgG4-Fc heavy-chain variant [3]

doi: 10.1016/j.neuroscience.2015.05.023 29 RojasMChavez-CastilloMBautistaJOrtegaANavaMSalazarJet al

Breast cancer occurred in an individual randomized to liraglutide 1.8 mg and treated with 2.4 mg at the time of the event, which was reported after 465 days of treatment

The safer takeaway is that GLP1 medications may affect some of the same systems involved in reward, appetite, metabolism, and self-regulation