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Circulating biomarkers for diagnosis and response to therapies in cancer patients

As of 2025, Retatrutide has completed Phase 2 trials with landmark results and is currently in Phase 3 trials

Meanwhile, the gene level of matrix metallopeptidase nine and tumor necrosis factor related to tumor metastasis exhibits a downward trend in SLC25A22-silenced cancer cells, indicating inhibition of GSH synthesis may play a critical role in the treatment of cancer metastasis (Wong et al., 2016)

Injections of Glutathione does translate into elevated levels of Glutathione in the blood however this method is undesirable on a daily basis, is expensive and inconvenient