In one study of infertile women, the incidence distribution was surprisingly robust for minimal-to-mild cases at 68%, whereas women with moderate-to-severe disease constituted the remaining 32% (24)
The research is solid: Stimulates collagen and elastin synthesis Promotes angiogenesis (new blood vessel formation) Increases fibroblast activity (the cells that rebuild skin) Modulates metalloproteinases (enzymes that remodel tissue) Has anti-inflammatory properties (in healthy tissue) Sounds perfect for acne scarring, right
The Swedish Obesity Subjects Study from 2007 evaluated over 4,000 patients in a prospective matched control study and demonstrated improvements in mortality, mostly due to reduction in death from cancer and myocardial infarction, of up to 2030% based on the degree of obesity prior to surgery with sustained outcomes at 1015 years of follow-up [21]
Furthermore, in rat models, the GLP-1 RA exendin-4 was found to alleviate ischemiareperfusion injury in skin flaps by upregulating Gpx4 expression, thereby inhibiting ferroptosis [73]