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At the same time, because of their lipophilic properties, many dietary antioxidant supplements can pass through the BBB and play an important biological role in the CNS 18

Symptoms of glutathione synthetase deficiency may include: Seizures Hampered reaction to speech and physical stimuli Poor coordination Intellectual disability Vulnerability to bacterial infections Low glutathione levels are also associated with a large number of disorders, including some types of cancer and AIDS

Early alterations in a mouse model of Rett syndrome: the GABA developmental shift is abolished at birth

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