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Castrec, B

Macrophage Cell Death and Efferocytosis Influence Plaque Stability The necrotic core results from a combination of accelerated macrophage death and impaired efferocytosis (receptor-mediated phagocytosis of apoptotic cells) (Figure 5) (171,172)

It is not intended for human or animal administration, and must not be used for diagnostic, therapeutic, or clinical applications.

GLP-1 medications are typically considered for adults who: Have a Body Mass Index (BMI) of 30 or higher Have a BMI of 27 or higher with weight-related conditions such as diabetes or hypertension Have not achieved sustained weight loss through lifestyle modification alone These medications are intended for long-term weight management, not short-term or cosmetic weight loss